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Depo-Provera prevents pregnancy by inhibiting ovulation with the hormone progestin. This prevents an egg from being released into the tube, preventing pregnancy. Progestin also thickens cervical mucus to prevent sperm from reaching the egg. Each injection of Depo-Provera prevents pregnancy for 3 months. Injections are typically given every 13 weeks; however, the injection can be given up to two weeks early.
Common side effects of Depo-Provera include weight gain, changes in flow or length of menstrual periods, bloating, dizziness, headaches, abdominal discomfort or pain, and changes in mood.
With continued use, Depo-Provera may cause loss of menstrual periods. Typically, women may gain about 5 pounds per year during the first 3 years of use. Women that are overweight have a higher risk of weight gain. Switching to a healthier diet and regular exercise can help you manage weight gain.
Even with correct use, there may be a small chance of pregnancy. Depo-Provera does not increase the risk of birth defects.
Do not use Depo-Provera if you are pregnant, have breast cancer or a serious liver disease, or have unexplained vaginal bleeding.
Pfizer Manufacturing, Belgium
Also known as: Medroxyprogesterone, Provera, Depo-SubQ Provera, Medrogest, Veraplex, Sayana, Depo-Kare, Miprox