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Hycamtin 1 mg (Topotecan Hydrochloride) 10 cap



Treatment of oncologic diseases

10 capsules

  • Active ingredient - Topotecan

Indications of Hycamtin medicine

  • multicellular carcinoma of lung;
  • ovarian carcinoma;
  • persistent or recurrent cervical cancer which is not amenable to surgery and / or radiation therapy (IVB step), in a combination therapy with cisplatin.


  • hypersensitivity to topotecan or other components of the medicine;
  • pronounced inhibition of bone marrow function (neutrophil count - less than 1500 / mm and the number of platelets - less than 100,000 / ml);
  • pregnancy;
  • lactation period;
  • сhildren's age (lack of experience).
Taking of the medicine during pregnancy and breast-feeding period

Embryo and foetotoxic effect of Hycamtin have shown in experimental studies. As other cytotoxic agents, Hycamtin may adversely affect the fetus in the appointment of pregnant women.

It is necessary to advise women to use reliable methods of contraception during Hycamtin therapy and immediately inform the treating physician if pregnancy occurs. It is not known whether the medicine appears in breast milk, so in the period of treatment is recommended to stop breast-feeding.

Adverse effects

Long-term use does not cause an increase in the toxic effect of the medicine. Serious manifestations of cardiotoxicity, neurotoxicity, organ toxicity were not observed.

From hemopoiesis system: very often - neutropenia, febrile neutropenia, leukopenia, thrombocytopenia, and anemia; often - pancytopenia; rarely - pronounced bleeding due to thrombocytopenia.

Immune system: often - hypersensitivity reactions, including rash.

From the digestive system: very often - diarrhea, nausea, vomiting (including severe) pain in the abdomen, constipation, stomatitis, anorexia (including severe); often - hyperbilirubinemia.

Skin: very often - alopecia.

Others: very often - fever, fatigue, asthenia, accession secondary infections; often - weakness, sepsis; very rarely - ecchymosis, hemorrhage (mild and did not require specific treatment).




Also known as: Topotecan Hydrochloride for Injection, Topotec, Topocan, Topotel, Toranex, Topotecan Actavis, Verotekan, Potactasol


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