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Active ingredient - Clomipramine 25 mg
Manufacturer - Novartis Farma, S.P.A, Switzerland.
Anafranil is indicated for obsessive-compulsive disorders (OCD) treatment. According to the Diagnostic Statistical Manual of Mental Disorders (DSM-III-R 1989) obsessive thoughts and actions lead to severe overstrain, time consuming and greatly hinder of the patient’s social and professional activities. He has periodically arised some obsessions, thoughts, images or impulses of egodystonic kind. The response to them are constantly repeated deliberated and concerted actions that the patient admits as excessive and unreasonable.
Anafranil (clomipramine hydrochloride in USP capsules) is contraindicated for patients with demonstrated hypersensitivity to the Anafranil or otherwise tricyclic antidepressants. Anafranil should not be appointed simultaneously or within 14 days after receiving a monoamine oxidase inhibitors (MAOIs). Patients treated with drugs of such combinations have been reported seizures, a critical decrease of the body temperature, coma and death. Anafranil is not applied during the recovery after myocardial infarction.
The most frequent reactions (not marked by patients treated with placebo) were gastrointestinal disorders including dry mouth, constipation, nausea, indigestion, and anorexia. From the nervous system observed drowsiness, dizziness, limbs tremor, myoclonus and nervousness. With the genitourinary system accounted dysuria, libido changes, lack of ejaculation and impotence. Also documented fatigue, sweating, increased appetite and weight gain.
Known as: Clofranil, Klominal, Hydiphen, Maronil, Neoprex, Apo-Clomipramine, Clomicalm
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